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Not persisting with medication is a well known phenomenon with other conditions, such as type 2 diabetes, chronic obstructive pulmonary disease and hypertension
Ongoing monitoring and supportive care, including mental health followup, are essential
Nutritional support Personal meal plans powered by Wellis AI are built into the app experience
Standard semaglutide titration: Weeks 1-4: 0.25 mg weekly Weeks 5-8: 0.5 mg weekly Weeks 9-12: 1.0 mg weekly Week 13+: 1.7 mg or 2.4 mg weekly (target dose) Hashimoto's-adjusted approach: Weeks 1-6: 0.25 mg weekly (extended to allow thyroid monitoring at week 6) Weeks 7-12: 0.5 mg weekly (TSH check before increasing) Weeks 13-16: 1.0 mg weekly Week 17+: Assess whether higher doses are needed The extended timeline allows for thyroid function checks at each step, ensuring levothyroxine doses are adjusted proactively rather than reactively
Kirkman HN, Gaetani GF
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